America’s Poison Facilities reported practically 3,000 calls this yr involving the burden loss drug semaglutide—a 15-fold enhance since 2019, based on CNN.
Among the folks calling described signs associated to unintentional overdose. Those that wanted to be hospitalized normally recovered as soon as they obtained fluids and nausea meds.
Permitted by the U.S. Meals and Drug Administration in 2017, semaglutide is bought as Ozempic to deal with diabetes and as Wegovy for weight reduction.
As soon as celebrities began touting the drug’s weight reduction effectiveness on social media final yr, the general public’s demand for semaglutide brought about a scarcity of the drug nationwide.
This scarcity led the FDA to permit some pharmacies to make compounded variations of the drug, which frequently have been completely different from the patented model, CNN reported. Many contained semaglutide salts and weren’t examined or accepted as protected and efficient.
Regardless of this, the knock-offs are in demand as a result of they’re inexpensive.
Though there is no such thing as a manner for them to know for certain if the poison middle calls stemmed from the patented drug or the knock-offs, many state poison middle administrators instructed CNN they believed the compounded variations are accountable.
However how did folks by accident overdose?
Apparently, Ozempic and Wegovy arrive in safeguarded, prefilled pins. You dial to the proper dose then click on to inject the medication.
The compounded variations, nonetheless, typically arrive in multidose vials and the medication should be drawn right into a syringe.
“That is the place we see numerous errors. They find yourself drawing an excessive amount of,” mentioned Dr. Joseph Lambson, director of the New Mexico Poison and Drug Data Middle.
One of many calls Lambson’s staff obtained was from a 37-year-old lady who by accident gave herself 1 milliliter as a substitute of 0.1 milliliter—10 occasions the beneficial quantity—as her first dose for weight reduction, CNN reported.
With the name-brand variations, the dosage begins low and inreases, so your physique can get used to it.
That does not imply they’re fool-proof, nonetheless. Julie Weber, director of the Missouri Poison Middle, instructed CNN the middle obtained a name from a girl who misunderstood how the pen labored.
“They didn’t know how you can use it correctly and dialed it up too (excessive) and took, like, the entire pen as a substitute of simply the dose that was imagined to occur,” she mentioned. A pen is designed to final a month.
In response to the middle, indicators of a semaglutide overdose embrace:
- Feeling lightheaded or dizzy
- Feeling shaky or jittery
- Sweating, chills and clamminess
- Irritability or impatience
- Weak point
- Nausea and/or vomiting
- Passing out
Whether or not you’re taking the patented or the knock-off model, in the event you expertise any of those signs, name your native poison management middle.
©2023 The Atlanta Journal-Structure.
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Poison middle calls associated to injected weight-loss medication up 1,500% (2023, December 14)
retrieved 18 December 2023
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